What is pharmaceutical chemistry?
The beginning of this is considered by Friedrich Sertürner as the first isolation of a chemically homogeneous drug substance from plant material. This discipline deals with the structure of drugs, their physicochemical properties, methods of preparation including synthesis, effects on the human body, and qualitative and quantitative chemical evaluation. An important aspect with medicinal substances is to conduct research on the stability of drugs, i.e., resistance to physicochemical and biological factors.
Enzymes, environmental pH, as well as light and temperature are factors that can cause changes in the structure or properties of drugs. This can increase the toxicity of the preparations, as well as affect the pharmacological activity, which is weakened or completely lost. Therefore, qualitative, and quantitative analysis is an important element of research on medicinal substances, the results of which are compared with strictly defined standards for a particular drug and its forms. MT ROYAL CO with experience in this field are able to import and supply chemical and pharmaceutical raw materials with reasonable prices in short delivery time.
Natural origin Pharmaceutical Raw Materials
The branch of science that deals with pharmaceutical raw materials obtained from natural sources is called Pharmacognosy. is given.
Natural medicine raw materials that are the subject of pharmacognosy are called ‘drugs’; ‘Herbal drugs’ to natural medicine raw materials obtained from plants to those obtained from animals They are called ‘animal drugs’. Apart from these, drugs obtained from microorganisms, minerals The drugs obtained, and the pharmaceutical raw materials obtained by recombinant DNA technology are also of natural origin. is one of the drugs.
Natural origin Pharmaceutical
Raw Materials:
· Herbal drugs
· Animal drugs
· Natural drugs of mineral (organic- inorganic) origin
· Microorganisms
· DNA recombination
Herbal drugs: The active ingredient is usually in a certain part of the plants (juice, leaf, rhizome, root, such as seeds or shells). They are obtained by extraction from here. herbal origin active ingredients chemically; basic substances (alkaloids) containing amine groups, fixed oils, gums, they have different structures such as carbohydrates, glycosides, and others.
Sometimes, it is not practical and economical to isolate the active substance from the plant in pure form; This Otherwise, the part of the plant prepared to contain the active substance in a standard amount is used as it is. or, as is often done, extractive forms (extract, liquid) containing the active substance in a concentrated form. extract, tincture, etc.) is prepared. Such preparations are called galenic preparations.
Animal drugs: Just like herbal medicines, they are either obtained as pure substances. or extracts containing concentrated active substance are prepared. animal-derived drugs The main ones are some hormones and enzymes.
Natural drugs of mineral (organic- inorganic) origin: A few drugs (sodium chloride, magnesium salts, potassium chloride and kaolin) obtained by purification from minerals in nature. they are made.
Microorganisms: Some microorganisms are the source of especially antibiotic drugs.
DNA recombination: These are drugs prepared with DNA technology. human interferons, interleukins, insulin, growth hormone, colony stimulating factors, and some vaccines with recombinant DNA technology is obtained.
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